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中文名甲钴胺英文名Mecobalamin别名甲钴胺甲基钴胺素甲钴胺水合物甲基维生素BVB(12)甲钴胺甲钴胺VB12 原料粉甲基钴胺素(-20℃)甲钴胺VB12,COΑ-[Α-(5,6-二甲基苯并咪唑基)]-Β甲钴酰胺英文别名AlgobazMecobalaminMECOBALAMINVitamin B12MECOBALAMINEMethylcobalaminMETHYLCOBALAMINMethyl Vitamin B12cobalt-methylcobalaminMethyl-5,6-dimethylbenzimidazolylcobalamincobinamide,cobalt-methylderivative,hydroxide,dihydrogenphosphate(ester),CAS13422-55-4EINECS236-535-3化学式C63H90CoN13O14P分子量1343.4InChIInChI=1/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;-1;+3/p-2/t31?,34-,35-,36-,37+,41+,52?,53?,56?,57+,59-,60+,61+,62+;;/m1../s1InChIKeyJEWJRMKHSMTXPP-WYVZQNDMSA-L熔点>190°C (dec.)水溶性Partially soluble in cold water, hot water.溶解度DMSO (Slightly), Methanol (Sparingly), Water (Slightly)酸度系数pK1:7.64(+1) (25°C)存储条件Sealed in dry,Store in freezer, under -20°C稳定性Light Sensitie敏感性Sensitive to light外观Solid颜色Dark Red物化性质本品为深红色晶体或结晶性粉末,易溶于水,微溶于乙醇,不溶于丙酮,见光不稳定MDL号MFCD00082483体外研究Methylcobalamin (CH3-B12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyanide is replaced by a methyl group. Methylcobalamin (CH3-B12) features an octahedral cobalt(III) centre. Methylcobalamin (CH3-B12) can be obtained as bright red crystals. From the perspective of coordination chemistry, Methylcobalamin (CH3-B12) is notable as a rare example of a compound that contains metal-alkyl bonds. Methylcobalamin (CH3-B12) is equivalent physiologically to vitamin B12, and can be used to prevent or treat pathology arising from a lack of vitamin B12 (vitamin B12 deficiency), such as pernicious anemia. Methylcobalamin (CH3-B12) is also used in the treatment of peripheral neuropathy, diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis. From Wikipedia.