对乙酰氨基苯酚103-90-2

对乙酰氨基苯酚103-90-2
别名: 4'-羟基乙酰苯胺;N-乙酰对氨基酚;对羟基乙酰苯胺;对羟基苯基乙酰胺;N-(4-羟基苯基)乙酰胺;4-乙酰胺基苯酚;醋氨酚;4-乙酰氨基酚;对乙酰氨基酚;扑热息痛;APAP
分子式: C8H9NO2
分子量: 151.16
熔点: 168-172°C
敏感性: 对光敏感
可溶性: 溶于水(14 g/l at 20 °C), 乙醇 (100 mM), 二甲基亚砜(100 mM), 甲醇(50 mg/ml), and 二甲基甲酰胺.
生化和生理学机理: Acetaminophen is a Cox-1, Cox-2, and Cox-3 (cyclooxygenase) inhibitor. Acetaminophen may be selective for Cox-3 (IC50 values are > 1000, > 1000, and 460 μM for murine Cox-1, murine Cox-2, and canine Cox-3, respectively). Acetaminophen is a widely used analgesic and antipyretic agent.