研发生产磷酸特地唑胺 替唑唑磷酸酯CAS: 856867-55-5原料生产供应仅供企业出口现货直销

手机版链接：https://m.trustexporter.com/cz12370388.htm
中文名磷酸特地唑胺英文名Tedizolid phosphate别名磷酸特地唑胺替唑唑磷酸酯磷酸特地佐利泰地唑胺磷酸盐磷酸特地唑胺(磷酸泰地唑胺)(R)-3-(4-(2-(2-甲基四唑-5-基)吡啶-5-基)-3-氟苯基)-5-羟甲基噁唑烷-2-酮磷酸酯(R)-3-(4-(2-(2-甲基四唑-5-基)吡啶-5-基)-3-氟苯基)-5-羟甲基F唑烷-2-酮磷酸酯英文别名Tedizolid phosphateTedizolid PhosphateTedizolid phosphate impurity A-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate(R) -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate(5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone(R) -3- (4- (2- (2- methyl-tetrazol-5-yl) pyridin-5-yl) -3-fluorophenyl) -5-hydroxymethyl-oxazolidin-2-one phosphate(R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogenphosphate(R)-(3-(3-fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate[(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphateCAS856867-55-5EINECS1592732-453-0化学式C17H16FN6O6P分子量450.32密度1.75±0.1 g/cm3(Predicted)熔点>235°C (dec.)沸点725.6±70.0 °C(Predicted)溶解度DMSO (Slightly, Sonicated)酸度系数1.81±0.10(Predicted)存储条件under inert gas (nitrogen or Argon) at 2-8°C稳定性Hygroscopic外观Solid颜色White to Off-White体外研究Tedizolid (TR-700, formerly torezolid)是前体药物tedizolid phosphate (TR-701)的活性部分，具有拮抗革兰氏阳性菌的活性，包括耐甲氧西林的金黄色酿脓葡萄球菌。Tedizolid在体外拮抗PRSP的效力是linezolid的4倍多。体内研究Tedizolid具有良好的肺上皮黏液层渗透性。通过口服途径或静脉注射给药，Tedizolid phosphate在体内可有效地拮抗系统性感染。口服Tedizolid phosphate还可有效拮抗由PSSP菌株所诱导的肺炎。