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万国企业网 » 产品供应 » 医疗 » 医药中间体 » 研发生产甲磺酸罗哌卡因 罗哌卡因甲磺酸盐CAS: 854056-07-8原料供应仅供出口现货直销

研发生产甲磺酸罗哌卡因 罗哌卡因甲磺酸盐CAS: 854056-07-8原料供应仅供出口现货直销

发布日期 ：2023-11-22 20:10 编号：12354785 发布IP：115.206.199.241
研发生产甲磺酸罗哌卡因 罗哌卡因甲磺酸盐CAS: 854056-07-8原料供应仅供出口现货直销
研发生产甲磺酸罗哌卡因 罗哌卡因甲磺酸盐CAS: 854056-07-8原料供应仅供出口现货直销研发生产甲磺酸罗哌卡因 罗哌卡因甲磺酸盐CAS: 854056-07-8原料供应仅供出口现货直销研发生产甲磺酸罗哌卡因 罗哌卡因甲磺酸盐CAS: 854056-07-8原料供应仅供出口现货直销
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中文名甲磺酸罗哌卡因
英文名Ropivacaine mesylate
别名甲磺酸罗哌卡因
罗哌卡因甲磺酸盐
甲磺酸罗哌卡因中间体
S-罗哌卡因甲磺酸盐
甲磺酸罗哌卡因854056-07-8
N-(2,6-二甲基苯基)-1-丙基哌啶-2-甲酰胺甲磺酸盐
N-(2,6-二甲基苯基)-1-正丙基哌啶-2-甲酰胺甲磺酸盐
(S)-N-(2,6-二甲基苯基)-1-丙基-2-哌啶酰胺甲磺酸盐
S-(-)-N-(2,6-二甲基苯基)-1-丙基-2-哌啶甲酰胺甲磺酸盐
英文别名ROPIVACAINE MESYLATE
Ropivacaine mesylate
S-Ropivacaine mesylate
(S)-Ropivacaine Mesilate
Ropivacaine Mesylate API
Ropivacaine Mesylate Injection
TIANFUCHEM--854056-07-8--Ropivacaine mesylate in stock
(S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamidemethanesulfonate
(2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide monomethanesulfonate
Ropivacaine mesylate (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide monomethanesulfonate
CAS854056-07-8
EINECS264-407-7
化学式C18H30N2O4S
分子量370.51
InChIInChI=1/C17H26N2O.CH4O3S/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;1-5(2,3)4/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H3,(H,2,3,4)/t15-;/m0./s1
体内研究Epidural administration of Ropivacaine mesylate effectively blocks neuropathic pain (both mechanical allodynia and heat hyperalgesia) without induction of analgesic tolerance and significantly delays the development of neuropathic pain produced by peripheral nerve injury. Ropivacaine mesylate inhibits pressure-induced increases in filtration coefficient (Kf) without affecting pulmonary artery pressure (Ppa), pulmonary capillary pressures (Ppc), and zonal characteristics (ZC). Ropivacaine mesylate prevents pressure-induced lung edema and associated hyperpermeability as evidence by maintaining PaO2, lung wet-to-dry ratio and plasma volume in levels similar to sham rats. Ropivacaine mesylate inhibits pressure-induced NO production as evidenced by decreased lung nitro-tyrosine content when compared to hypertensive lungs. Animal Model: Adult Sprague-Dawley rats (300-400g) Dosage: 1 μM Administration: Infusion (added to the perfusate reservoir) Result: Attenuated pressure-dependent increases in filtration coefficient (K f ).



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